The DKFZ/NCT/DKTK MASTER (Molecularly Aided Stratification for Tumor Eradication) Program is a central platform for multidimensional characterization of patients with advanced rare cancers, as well as patients diagnosed with an incurable common malignancy at an unusually early age, seen at NCT Heidelberg, NCT Dresden, or one of the sites of the German Cancer Consortium (DKTK; Berlin, Essen/Düsseldorf, Frankfurt/Mainz, Freiburg, Munich, Tübingen).
The goal of this multidisciplinary effort is to enable clinically meaningful precision cancer medicine by applying current and future technologies that capture the molecular, cellular, and functional properties of individual human tumors in an integrated fashion. To this end, a team of physicians, biologists, study nurses, documentalists, and scientific/administrative coordinators in the Departments of Translational Medical Oncology (TMO) at NCT Heidelberg and NCT Dresden; the Computational Oncology Group and the Sample Processing Laboratory (SPL) of the NCT Molecular Diagnostics Program; the DKFZ Genomics and Proteomics Core Facility (GPCF); the DKFZ Omics IT and Data Management Core Facility (ODCF); as well as investigators at the Institute of Pathology Heidelberg and the Departments of Human Genetics at NCT Dresden and Heidelberg University Hospital work jointly on strategies for rapid-turnaround molecular profiling and streamlined data acquisition and analysis in a clinical setting.
NCT/DKFZ/DKTK MASTER Workflow
DKFZ/NCT/DKTK MASTER enables clinical investigators to rapidly implement noval molecular analyses in the patient context.
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Clinical Translation
Swift translation of innovative high-throughput diagnostics into clinical practice.
